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Principal Scientist / Associate Director, FBDD
Location:
San Diego, CA
Description:
Our Ideal Candidate: You are a skilled biophysical assay scientist with a passion for undruggable targets and deep expertise in fragment-based drug discovery. You thrive in a multidisciplinary team environment and are excited about making an impact in the rapidly evolving field of targeted protein degradation. Responsibilities: This is an individual contributor position which will play a key role within our Molecular Sciences department, applying gold standard and cutting-edge biophysical screening technologies to the discovery of new chemical matter in complex systems. Stay up to stay on the latest technologies, make recommendations on appropriate fragment based screening equipment, set up and maintain equipment. Assay development, optimization, and data collection for the purposes of fragment identification and validation, SAR studies, and mechanism of action studies using various assay formats. Assay types of interest include both protein-ligand and protein-protein interaction techniques, including but not limited to SPR, GCI, DSF, ASMS, MST, proximity, and enzymatic activity assays, among other biochemical and biophysical approaches. May be responsible for additional external assay development and screening efforts. Work closely with chemists to rapidly advance early projects as part of a team. Required Education: Senior Scientist level: PhD in Biochemistry, Biophysics, or a related field with 5+ years, MS with 8+ years or BS with 11+ years of relevant experience Principal Scientist level: PhD in Biochemistry, Biophysics, or a related field with 8+ years, MS with 11+ years or BS with 14+ years of relevant experience Associate Director level: PhD in Biochemistry, Biophysics, or a related field with 10+ years, MS with 13+ years or BS with 16+ years of relevant experience Required Qualifications: Deep and broad experience in developing, troubleshooting, and executing high quality biochemical and biophysical screens in multiple formats (including SPR, GCI, ASMS, MST, DSF, AlphaScreen, HTRF etc) Ability to use typical lab automation equipment including dispensers, multimode plate readers, etc. Ability to optimize and miniaturize assays to enable HTS. High proficiency with LIMS platforms and analytical software including Prism, Microsoft Excel, etc. Demonstrated experience in advancing small molecule discovery projects through lead identification and optimization as part of a multidisciplinary team Preferred Qualifications: Experience working in the targeted protein degradation field or with “undruggable” targets a plus What we offer: Industry competitive compensation Annual target bonus Stock options 401K plan Career advancement opportunities Monthly town halls to share business and scientific updates Work Hard, Stay Well Comprehensive medical, dental, and vision plans for employees and their dependents Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution Employee Assistance Program 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave. Supplemental pay for Pregnancy Disability Leave Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care Lifestyle Casual work environment Volunteer days off each year to spend time contributing to causes you care about Flexible work schedule Access to onsite gym Onsite space to store your bicycle (or surfboard) Have Fun! We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day). About Us: Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets’. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.Neomorph is headquartered in San Diego, California, and has a key collaboration with the Center for Protein Degradation at the Dana-Farber Cancer Institute.Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state or local law.
Company:
Neomorph
Posted:
March 26 on AlphaStaff Hiring
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More About this Listing: Principal Scientist / Associate Director, FBDD
Principal Scientist / Associate Director, FBDD is a Executive Associate Director, Scientist Job at Neomorph located in San Diego CA. Find other listings like Principal Scientist / Associate Director, FBDD by searching Oodle for Executive Associate Director, Scientist Jobs.
Principal Scientist / Associate Director, FBDD is a Executive Associate Director, Scientist Job at Neomorph located in San Diego CA. Find other listings like Principal Scientist / Associate Director, FBDD by searching Oodle for Executive Associate Director, Scientist Jobs.